This image depicts the chemical structure of cytosine. It shows a hexagonal ring with nitrogen atoms at positions 1 and 3, and a primary amine group attached to carbon 4. The two remaining positions ...

Inside human cells, biology has pulled off the ultimate packing job, figuring out how to fit six feet of DNA into a nucleus ...

Supercoiling and looping can transmit mechanical stress along the DNA backbone that can promote the separation of the strands of the double helix at specific distant sites, exposing the DNA bases, ...

A change in the DNA sequence of a codon may not change the corresponding amino acid residue in the encoded protein because each residue can be encoded by several codons. This is called the Wobble ...

Fluorogenic DNA aptamers produce light only in the correct structural state, enabling programmable molecular logic, ...

Inside every human cell, six feet of DNA folds into a nucleus that is only a few micrometers wide, yet still manages to switch genes on and off with exquisite precision. The latest work on ...

Studying how single DNA molecules behave helps us to better understand genetic disorders and design better drugs. Until now however, examining DNA molecules one-by-one was a slow process.

As one of the inventors of next-generation DNA sequencing, Sir Shankar Balasubramanian could claim to be responsible for a revolution in the life sciences. Balasubramanian and chemist David Klenerman, ...

By the time James Watson died earlier this month at the age of 97, he was one of the world’s most famous — and infamous — scientists. In 1953, he and three fellow researchers co-discovered the ...